Morecambe town centre's branch is on a list of post offices earmarked for possible closure.
More than 1,000 staff across the UK could lose their jobs in a radical shake-up as the Post Office laid out plans to stabilise its finances.
The Communication Workers Union (CWU) representing Post Office staff has hit out at proposals, describing them as "immoral".
The Post Office is looking at options for the future of its business. One option is the closure of up to 115 branches, said to be loss-making, including the site at Victoria Street in Morecambe town centre.
Proposals aim to place postmasters at the heart of the government-owned business in the wake of the highly-publicised Horizon IT scandal.
This saw sub-postmasters wrongly jailed after faulty computer software made it appear as though money was missing from their accounts.
Their ongoing fight to secure redress and compensation was highlighted on the award-winning TV drama 'Mr Bates versus The Post Office'.
Alternative franchise arrangements could see an operator like WH Smith or another third party take on the branches.
In 2016, Lancaster's General Post Office on the corner of Meeting House Lane and Fenton Street closed down and services moved to WH Smith on Market Street.
"CWU members are victims of the Horizon scandal - and for them to now fear for their jobs ahead of Christmas is yet another cruel attack", said Dave Ward, general secretary of the CWU.
"While we are in the middle of a government review of the Post Office's future, the employer has embarked on its own strategic review.
"It seems the Post Office has learned no lessons from its chaotic and uncoordinated mistakes of the past.
"We call on the Post Office to immediately halt these planned closures and the attached consultations - which, historically, have been nothing but playing lip service - and engage with the CWU on protecting jobs and services.
"We also call on the government to intervene over this shambolic decision."
A strategic review of the Post Office business was called in May, by new chairman Nigel Railton.
He told staff on Wednesday that postmasters could expect up to £120m in additional remuneration by the end of the first year of the plan, representing a 30 per cent increase in revenue share.
This would tackle long-held complaints about poor rewards for postmasters' work, and there were also promises of lless red tape and a better voice in decision-making.
Mr Railton said: "The Post Office has a 360-year history of public service and today we want to secure that service for the future by learning from past mistakes and moving forward for the benefit of all postmasters. We can, and will, restore pride in working for a business with a legacy of service, rather than one of scandal.
"The value postmasters deliver in their communities must be reflected in their pockets, and this Transformation Plan provides a route to adding more than £250m annually to total postmaster remuneration by 2030, subject to government funding.
"It begins a new phase of partnership during which we will strengthen the postmaster voice in the day-to-day running and operations of the business, so they are represented from the frontline to the boardroom."
Kendal Post Office is also on the list of branches under threat.
A spokesperson for the Department for Business and Trade said: "The government is in active discussion with Nigel Railton on his plans to put postmasters at the centre of the organisation and strengthen the post office network for its long-term future."
Appeal launched to help save Morecambe sports and social club
Reopening date announced after Morecambe Jobcentre closes for repairs
Lancaster charity urges residents to know how they’re affected by Renters' Rights Act
Lancaster district residents urged to check their details as annual electoral canvass begins
E-bikes and e-scooters seized during police crackdown on Lancaster cycle track
Four vehicles involved in road collision in Carnforth
LISTEN: Popular vlog tells story of couple's second-hand bookshop dream in Morecambe
Emergency team in Silverdale receives donation of life-saving kits
MP offers support to staff after Morecambe FC reported to The Pensions Regulator
Track night at Lancaster sports club to launch police safety scheme for women and girls
PHOTOS: Live music day to raise funds for homeless people in Lancaster hailed as huge success
Former bank turned live music venue in Morecambe to reopen under new management
New parking system set to launch at Royal Lancaster Infirmary
Museum in Lancaster up for award launched by TV historian David Olusoga
MP fights for refunds after Heysham medical centre patients get parking fines in error
Two teenagers arrested after car stolen during Hest Bank burglary
Parents demand further action after health watchdog probe into asbestos complaints at Lancaster school
LISTEN: Lancaster medical students praised for helping man who collapsed
Man arrested on Morecambe beach after report of assault
Police probe burglaries in villages near Carnforth
